nuclear lamina การใช้

• The nuclear lamina is composed mostly of lamin proteins.
• Nuclear lamina exist in all animals and all tissues.
• Structure and function of the nuclear lamina.
• Nuclear LC3 interacts with lamin B1, and participates in the degradation of nuclear lamina.
• Various experiments show that the nuclear lamina plays a part in the elongation phase of DNA replication.
• Apoptosis is a highly regulated process in which the nuclear lamina is disassembled in an early stage.
• The nuclear lamina is similar in structure to the nuclear matrix, but the latter extends throughout the nucleoplasm.
• The non-random organization of the genome strongly suggests that the nuclear lamina plays a role in chromatin organization.
• Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family.
• Nup98 seems to be responsible for the transport of many RNAs from the center of the nucleus to the nuclear lamina.
• Intermediate filaments organize the internal tridimensional structure of the cell, anchoring organelles and serving as structural components of the nuclear lamina.
• Several proteins have been found to be prenylated and methylated at their nucleus, where it partially colocalizes with the nuclear lamina.
• Due to their positioning within or their association with the inner membrane, they mediate the attachment of the nuclear lamina to the nuclear envelope.
• The nuclear lamina is associated with the inner face of the double bilayer nuclear envelope, whereas the outer face is continuous with the endoplasmic reticulum.
• Barrier to autointegration factor ( BAF ) is a chromatin-associated protein that also binds to the nuclear lamina and several of the aforementioned nuclear envelope proteins.
• Towards the end of the cell cycle, the nuclear membrane is reformed, and around the same time, the nuclear lamina are reassembled by dephosphorylating the lamins.
• Not only nuclear lamina associated lamins are present during replication, but free lamin polypeptides are present as well and seem to have some regulative part in the replication process.
• Like all proteins, lamins are synthesized in the cytoplasm and later transported to the nucleus interior, where they are assembled before being incorporated into the existing network of nuclear lamina.
• Lamin A is a major component of a protein scaffold on the inner edge of the nucleus called the nuclear lamina that helps organize nuclear processes such as RNA and DNA synthesis.
• "' Laminopathies "'( "-opathy " ) are a group of rare genetic disorders caused by mutations in genes encoding proteins of the nuclear lamina.